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Ginkofar Coated tablets Composition  Each tablet contains 40 mg of the dry extract from Ginkgo bilobae leafs, containing 24% ginkgoflavoglycosydes, 6 % terpene lactones and the following auxiliary substances: lactose, polyvinylpirolidone, polyethylene glycol, hydroxypropylmethylocellulose, magnesium stearate, titanium dioxide, colloidal silica, ferrous oxide.
Mechanism of action  The combination of the active substances contained in the dry extract obtained form Ginkgo bilobae increases tissue tolerance, including brain tissue, to ischemia. This combination abolishes vasoconstriction, decreases blood viscosity and platelet aggregation, leading to increased blood flow through the tissue microvessels. Extract obtained from Ginkgo bilobae neutralizes free radicals and exerts neuroprotective activity. It is observed that the extract slightly attenuates the course of Alzheimer's disease and glaucoma. Clinical activity of Ginkofar consists of decreasing cerebral ischemia, improving cerebral blood flow and peripheral blood flow through lower extremities, protection of the cell against hypoxia, inhibition of platelet aggregation and increasing blood fluidity.
Therapeutical indications Ginkofar is used in cases of cerebral and peripheral blood flow disturbances, atherosclerosis and associated symptoms such as difficulty in concentration and memory disturbances, vertigo and headaches, tinnitus, impaired blood supply to lower extremities (feeling of cold and pain of the feet), impaired hearing and sight. Undesirable effects Gastrointestinal disturbances are rarely observed. In particularly sensitive persons headache and skin allergic reactions may occur. Warnings and precautions The drug is safe and its intake does not require any particular precautions. Use during pregnancy and lactation No adverse effects of the Ginkgo bilobae extract to the foetus or newborn are known. However, because of general medical reasons, Ginkofar should not be used during pregnancy or lactation Influence on ability to drive and operate machinery Ginkofar does not exert negative effects on ability to drive Undesirable effects Gastrointestinal disturbances are rarely observed. In particularly sensitive persons headache and skin allergic reactions may occur. Overdose Following single or repeated overdose, gastrointestinal disturbances, flight of ideas and headache may occur. Contraindications Allergy to any of the drug components, poor drug tolerance. Dosage and administration Ginkofar is for oral use, taken one tablet three times daily after a meal with some liquid. Therapy should last for 8-12 weeks. The first symptoms of improvement are usually seen after four weeks of therapy. Following substantial therapy, further treatment (1 tablet taken two times daily) is recommended. Ginkofar is well tolerated and may be used for prolonged periods. Available packages Cartoons containing 20, 60 or 90 tablets. | 
